Anxiety Disorders (Adult) Research Study
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1. Understanding the Brain & Body Responses Associated with Anxiety Disorders
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Several research studies seek to learn about brain and body responses associated with generalized anxiety disorder.Recruiting adults, ages 18-50, to participate in several outpatient visits to the NIH Clinical Center in Bethesda, Maryland. Eligible participants must have anxiety symptoms, be medically healthy and not currently taking psychiatric medication or abusing alcohol or other substances. Participation includes having psychiatric interviews, psychological testing, brain imaging, medical history and a physical exam. There is no cost for participation or any tests associated with the research. Financial compensation is available for participation. This study enrolls participants locally from within 50 miles of NIH.Call toll free: 1-888-644-2694 (1-888-NIH-ANXI) TTY: 1-866-411-1010, E-mail:anxiety@mail.nih.gov
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Disease and Treatment Information |
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Anxiety Disorders (Adult) Research Study
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2. Generalized Anxiety Disorder and Social Anxiety Disorder: Their impact on the processing of social emotional information and instrumental learning
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If you consider yourself to experience more anxiety or are shyer than those around you or have been diagnosed with generalized anxiety disorder or social anxiety disorder, you may be able to participate in this study examining how the brain responds to and analyzes emotional events.
Our goal is to understand what is special about the brain response to emotional events in people with anxiety disorders. We assess brain responses with both computer tasks and brain imaging (functional Magnetic Resonance Imaging; fMRI). Healthy volunteers who have no history of psychiatric or major medical illness will also be enrolled in this study.
To find out if you qualify or for more information, please call (301) 496-5645 or email us at nimhcore@mail.nih.gov.
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Protocol Information |
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Anxiety Disorders (Adult) Research Study
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3. Predictability and Aversive Expectancies in Anxiety Disorders
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If you consider yourself to experience more anxiety than those around you or have been diagnosed with generalized anxiety disorder, social anxiety disorder, panic disorder, or specific phobia, you may be able to participate in this study examining changes in the body and brain that occur during fear and fear learning.
Basic research has identified biological processes that play a key role in fear and anxiety. The present study examines such processes across those with and without elevated levels of anxiety to better understand the biological basis of anxiety disorders. More specifically, we will be assessing changes in heart rate (EKG), muscle activity (EMG), sweat responses (SCR) and respiration that occur during exposure to mildly unpleasant events. Healthy volunteers who have no history of psychiatric or major medical illness will also be enrolled in this study.
To find out if you qualify or for more information, please call (301) 496-5645 or email us at nimhcore@mail.nih.gov.
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Protocol Information |
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Anxiety Disorders (Adult) Research Study
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4. Effects of D-Cycloserine on Treatment in Social Anxiety
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This study examines whether an antibiotic, d-cycloserine (DCS), boosts the effectiveness of cognitive behavior therapy (CBT) for social anxiety. CBT has been shown to be effective for the treatment of social anxiety in children and adults, but even after treatment, approximately 40% may remain diagnosable.
All participants will receive 12 weekly CBT sessions. In addition to receiving the CBT, participants will be randomly assigned (similar to a coin toss) to receive either DCS or a placebo (sugar pill). The pill will be taken 1-2 hours prior to each of the 12 CBT sessions. The pill is taken only on the 12 therapy days. If you are ages 7-55 with a social phobia, you may be eligible for the study.
To find out if you qualify or for more information, please call (301) 496-5645 or email us at nimhcore@mail.nih.gov.
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Protocol Information |
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Anxiety Disorders (Adult) Research Study
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5. NIMH Family Study of Health and Behavior
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The major goal of this study is to examine how mood disorders, anxiety disorders and migraine run in families. We study both genetic and environmental factors that may contribute to these conditions.
We recruit people ages 21 and over with depression, manic-depression, social phobia, panic, generalized anxiety, migraine and people without any of these problems. Participants are interviewed about medical and mental symptoms and problems, their health behavior, social factors and a variety of other measures related to their health and behavior. Family members ages 8 and over will also be asked to participate. Some families will be invited to participate in further studies of biological and genetic factors.
To find out if you qualify or for more information, please call 1-877-250-1560 or email at familystudy@mail.nih.gov.
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Protocol Information |
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